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NTRA US​

Natera, Inc.(NTRA US)

Overview

ProfileEntity Structure

Documents

SEC Filings

Financials & Metrics

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Natera, Inc. — Company Profile

Natera, Inc. is a diagnostics company focused on developing and commercializing a wide array of molecular testing services globally. Its portfolio includes several key offerings: Panorama, a non-invasive prenatal test (NIPT) that screens for chromosomal abnormalities in a fetus using a blood sample from the mother, and also determines zygosity in twin pregnancies. Vistara, designed to identify single-gene disorders by screening for specific single-gene mutations. Horizon, a comprehensive carrier screening test to determine an individual's carrier status for various genetic diseases. Spectrum, utilized during in vitro fertilization (IVF) cycles to detect chromosomal anomalies or inherited genetic conditions. Anora, a miscarriage analysis product that examines fetal chromosomes to help understand the cause of pregnancy loss. Non-invasive paternity testing, which establishes paternity during gestation using blood samples from both the pregnant mother and the alleged father. Beyond reproductive health, Natera also provides specialized tests: Signatera, a sophisticated circulating tumor DNA (ctDNA) technology capable of screening for a generic set of mutations, independent of the individual's specific tumor characteristics. Prospera, a test used to assess and monitor organ transplant rejection. Additionally, the company offers Constellation, a cloud-based software platform that provides laboratory clients with access to Natera's proprietary algorithms and bioinformatics, enabling them to validate and launch their own tests. Natera distributes its products through a direct sales team and an extensive network of approximately 100 laboratory and distribution partners. The company has strategic partnerships, including one with BGI Genomics Co., Ltd. for the development, manufacturing, and commercialization of NGS-based genetic testing assays, and another with Foundation Medicine, Inc. to develop and commercialize personalized circulating tumor DNA monitoring assays. Founded in 2003, Natera, Inc. is headquartered in Austin, Texas. It was formerly known as Gene Security Network, Inc. before changing its name in 2012.

Sector
Health Care
Industry
Health Care Equipment & Supplies
Exchange
UQ
CEO
Steven Leonard Chapman
Headquarters
Austin, TX, US
IPO Date
Jul 1, 2015
Employees
6,138
Website
www.natera.com

Key Metrics

Price
$410.35
Market Cap
$58.77B
Revenue (TTM)
$696.64M
Net Income (TTM)
$-85091000.00
EPS (TTM)
-0.60
P/E (TTM)
-259.67
P/B (TTM)
33.13
Dividend Yield
0.00%
ROE (TTM)
-4.80%
ROA (TTM)
-3.25%
Operating Margin
-13.42%
Beta
1.04

Dividends

Last Dividend
$0.00
Last Yield
0.00%

Summary

Natera, Inc. is a diagnostics company focused on developing and commercializing a wide array of molecular testing services globally. Its portfolio includes several key offerings: Panorama, a non-invasive prenatal test (NIPT) that screens for chromosomal abnormalities in a fetus using a blood sample from the mother, and also determines zygosity in twin pregnancies. Vistara, designed to identify single-gene disorders by screening for specific single-gene mutations. Horizon, a comprehensive carrier screening test to determine an individual's carrier status for various genetic diseases. Spectrum, utilized during in vitro fertilization (IVF) cycles to detect chromosomal anomalies or inherited genetic conditions. Anora, a miscarriage analysis product that examines fetal chromosomes to help understand the cause of pregnancy loss. Non-invasive paternity testing, which establishes paternity during gestation using blood samples from both the pregnant mother and the alleged father. Beyond reproductive health, Natera also provides specialized tests: Signatera, a sophisticated circulating tumor DNA (ctDNA) technology capable of screening for a generic set of mutations, independent of the individual's specific tumor characteristics. Prospera, a test used to assess and monitor organ transplant rejection. Additionally, the company offers Constellation, a cloud-based software platform that provides laboratory clients with access to Natera's proprietary algorithms and bioinformatics, enabling them to validate and launch their own tests. Natera distributes its products through a direct sales team and an extensive network of approximately 100 laboratory and distribution partners. The company has strategic partnerships, including one with BGI Genomics Co., Ltd. for the development, manufacturing, and commercialization of NGS-based genetic testing assays, and another with Foundation Medicine, Inc. to develop and commercialize personalized circulating tumor DNA monitoring assays. Founded in 2003, Natera, Inc. is headquartered in Austin, Texas. It was formerly known as Gene Security Network, Inc. before changing its name in 2012.

Website
www.natera.com
Location
Austin, TX, US
Phone650 249 9090
Employees6,138
CEOSteven Leonard Chapman
Sector
Health Care
Industry
Health Care Equipment & Supplies
IPO DateJul 1, 2015

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Latest Documents

SEC Filings(1.8K)

Expand
  • 4Sheena Jonathan23 Oct
  • 144Sheena Jonathan21 Oct
  • 4Sheena Jonathan20 Oct
  • 4Rabinowitz Matthew16 Oct
  • 144Rabinowitz Matthew15 Oct
  • 4Rabinowitz Matthew9 Oct
  • 4Chapman Steven Leonard2 Oct
  • 4Moshkevich Solomon2 Oct
  • 144Chapman Steven Leonard1 Oct
  • 144Moshkevich Solomon1 Oct
  • 4Sheena Jonathan25 Sep
  • 144Sheena Jonathan23 Sep
  • 4Moshkevich Solomon18 Sep
  • 4Sheena Jonathan17 Sep
  • 4Rabinowitz Matthew16 Sep
  • 144Rabinowitz Matthew15 Sep
  • 4Rabinowitz Matthew11 Sep
  • 144Rabinowitz Matthew11 Sep
  • 4Moshkevich Solomon3 Sep
  • 4Chapman Steven Leonard3 Sep

News

  • Here Are Friday’s Top Wall Street Analyst Research Calls: Deckers Outdoor, Globe Life, Guardant Health, Hess Midstream LP, Kimberly-Clark, Natera, NVR, SpaceX, Thermo Fisher Scientific, and More23 Oct
  • Biotech Giants vs. Emerging Innovators: Which ETF Is the Better Buy?22 Oct
  • Natera Partners With TransCode to Advance Colorectal Cancer Trial21 Oct
  • 2,138 Natera, Inc. $NTRA Shares Acquired by SteelPeak Wealth LLC19 Oct
  • ESMO 2026 Presentations Deepen the Evidence Base for Natera's Oncology Portfolio and Leadership in Ultrasensitive MRD Technology18 Oct
  • ESMO 2026 Presentations Deepen the Evidence Base for Natera's Oncology Portfolio and Leadership in Ultrasensitive MRD Technology18 Oct
  • Natera (NTRA) Price Forecast: Bullish Trend Holds as Next Leg Looms15 Oct
  • Natera's Signatera™ MRD Test Named to TIME's List of the Best Inventions of 202615 Oct
  • Natera's Signatera™ MRD Test Named to TIME's List of the Best Inventions of 202615 Oct
  • Natera Gains 118.1% in a Year: What's Driving the Rally?15 Oct
  • Natera and TransCode Therapeutics to Collaborate on Phase 2a Trial of TTX-MC138 in Colorectal Cancer13 Oct
  • Natera and TransCode Therapeutics to Collaborate on Phase 2a Trial of TTX-MC138 in Colorectal Cancer13 Oct
  • Which Healthcare ETF Is the Better Buy: Fidelity’s Broad FHLC or Invesco’s Biotech-Focused PBE?11 Oct
  • FDA Grants Breakthrough Device Designation for Natera's Multi-Cancer Early Detection Assay9 Oct
  • HWG Holdings LP Makes New $9.82 Million Investment in Natera, Inc. $NTRA8 Oct
  • Natera Announces Randomized, Signatera™-Guided Interventional Study in Melanoma7 Oct
  • Natera (NASDAQ:NTRA) Hits New 12-Month High – Here’s Why6 Oct
  • New Signatera™ Data Presented at ASTRO Conference, Highlights Utility for Radiation Oncologists6 Oct
  • New Signatera™ Data Presented at ASTRO Conference, Highlights Utility for Radiation Oncologists6 Oct
  • Alliance Foundation Trials and Natera Announce AFT-70 NAVIGATE: a Global, Randomized, Phase III Trial Evaluating Genentech's Oral Selective Estrogen Receptor Degrader (SERD) with Signatera™ MRD-Guided CDK4/6 Inhibitor Therapy in Breast Cancer5 Oct

Mentions in Filings

  • … WEBINAR WILL START SOON Participants Jacob Lalezari M.D. Chief Executive Officer of CytoDyn Robert E. Hoffman Chief Financial Officer of CytoDyn Pashtoon M. Kasi M.D., M.S. Medical Director of GI Oncology, City of Hope Orange County, Irvine, California Reny Aniline Sr. Director of BioPharma Business Development, Oncology & RWD Solutions, <strong>Natera</strong> --- Company Logo The Next Generation of Monoclonal Antibody Therapy CYTODYN.COM / OTCMKTS: CYDY ---
    CytoDyn Inc.Natera, Inc.·DEFA14A - Definitive additional materials·Q2 27·19 Oct
  • CLOVER – ctDNA % Change at Week 2 Based on Sig<strong>natera</strong> Exome\* Median decrease: 86% Patients with Data Available in September 2026 (n=28) \*Analysis includes all available Signatera Exome ctDNA measurements within seven days of starting treatment --- CLOVER – ctDNA % Change at Week 2 Based on Signatera Exome\* 350 mg Cohort (n=14) 700 mg Cohort (n=14) Median decrease: 80% Median decrease: 90% Patients with Data Available in September 2026 \*Analy …
    CytoDyn Inc.Natera, Inc.·EX-99.2 - 8-K - Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers: Compensatory Arrangements of Certain Officers·Q2 27·19 Oct
  • … eimbursement from Medicare, Medicaid. I suspect over time, commercial payers will start to pay more for these tests. They’re still radically underpaying. I think others have said the same thing, whether that’s Guardant or <strong>Natera</strong> so I think that’s a pretty common supposition at this point, which means I think you’re going to see margins in this space from the top providers that get extraordinarily high, one could argue too high. Long-term I think …
    Personalis, Inc.Natera, Inc.·425 - Business combination communication·Q3 26·15 Sep
  • … to estimated calendar year 2028 revenues (which is referred to as 2028E Revenue), based on consensus research estimates. The companies used in this comparison included the following companies: | | | | --- | --- | | • | <strong>Natera</strong> Inc. | | | | | --- | --- | | • | Guardant Health, Inc. | | | | | --- | --- | | • | Tempus | | | | | --- | --- | | • | BillionToOne Inc. | | | | | --- | --- | | • | Caris Life Sciences, Inc. | | | | | --- | --- | | • …
    Personalis, Inc.Natera, Inc.·DEFM14A - Definitive proxy statement (merger)·Q4 26·21 Oct
  • … | | | | | --- | --- | --- | | **Announcement Date** | **Target** | **Acquiror** | | April 28, 2026 | Naveris, Inc. | CareDx, Inc. | | December 5, 2025 | Foresight Diagnostics Inc. | <strong>Natera, Inc.</strong> | | November 20, 2025 | Exact Sciences Corporation | Abbott Laboratories | | April 27, 2023 | Haystack Oncology, Inc. | Quest Diagnostics Inc. | | November 3, 2022 | Immucor, Inc. | Werfen, S.A. | | October 31, 2022 | The Binding Site Group | Thermo Fishe …
    Tempus AI, Inc.Natera, Inc.·424B3 - Prospectus filing (Rule 424(b)(3))·Q4 26·21 Oct
  • … nologies Corporation | | | | | --- | --- | | • | BillionToOne, Inc. | | | | | --- | --- | | • | CareDx, Inc. | | | | | --- | --- | | • | Caris Life Sciences, Inc. | | | | | --- | --- | | • | GeneDx Holdings Corp. | | | | | --- | --- | | • | GRAIL, Inc. | | | | | --- | --- | | • | Guardant Health, Inc. | | | | | --- | --- | | • | <strong>Natera, Inc.</strong> | | | | | --- | --- | | • | Tempus AI, Inc. | | | | | --- | --- | | • | Veracyte, Inc. | 96 --- …
    Tempus AI, Inc.Natera, Inc.·S-4/A - Registration statement (business combination, amendment)·Q4 26·20 Oct

Key Stats

Trading

Px/Chg 1D$410.35 / +0.46%
Avg Volume1.44M
Beta1.04
Mkt Cap58.77B
FD Mkt Cap45.51B

Float

Shrs Out/Float143.22M / 136.92M
Short Float0.04%
Days to Cover2.75
Stock Repurchased$0.00

Current Valuation

EV57.92B
EV/EBITDA-258.85
EV/Sales23.16
P/B33.13
P/S23.50
FCF Yield0.03%
ROE-4.80%
ROA-3.25%
Current Ratio2.96

Estimates

P/E-259.67
Est P/EN/A
Est EPSN/A
Est PEGN/A

Valuation

Metric5Yr AvgMay '23May '24May '25May '26Oct '26
PRICE-BASED RATIOS
Price / Earnings-39.19-9.52-25.27-106.47635.96-690.65
Price / Sales31.606.3610.1511.9545.1684.36
Price / Book Value17.887.3914.3616.9617.5533.13
Price / Free Cash Flow859.40-10.88-38.40292.82794.723,258.75
ENTERPRISE VALUE METRICS
Enterprise Value24,522.65,195.810,787.919,516.929,192.257,920.4
Enterprise Value / Sales30.966.339.9711.5043.8783.14
Enterprise Value / EBITDA526.40-10.25-28.15-131.803,686.82-884.63
Enterprise Value / EBIT-1,109.06-9.67-25.57-109.01-4,725.19-675.85

Financials

Full Financials
Millions USD5Yr CAGR (%)Dec '21Dec '22Dec '23Dec '24Dec '25
INCOME STATEMENT
Revenue38.6%625.5820.21,082.61,696.92,306.1
Gross Income48.6%307.1364.0492.71,023.21,495.5
EBITDA-16.4%-451.5-507.0-383.3-148.1-220.5
EBIT-13.1%-462.8-537.5-421.9-179.0-264.0
Net Income-18.5%-471.7-547.8-434.8-190.4-208.2
EPS (Diluted)-26.5%-5.21-5.57-3.78-1.53-1.52
BALANCE SHEET
Cash & ST Inv4.2%914.3898.4879.0968.31,076.1
Total Assets19.3%1,236.51,394.51,441.71,660.72,508.0
Total Liabilities8.1%583.2688.7676.4465.3795.6
Total Shareholder Equity27.2%653.3705.7765.31,195.41,712.4
CASH FLOW
Net Operating Cash Flow—-335.2-431.5-247.0135.7215.3
Cap Ex26.8%-41.0-47.7-39.2-66.4-106.2
Free Cash Flow—-376.3-479.2-286.269.2109.1

Enterprise Value Bridge

Millions USD23 Oct '26
Price (As of 23 Oct '26)402.26
Basic Shares143.22
Market Cap57,609.7
Diluted Shares141.50
Fully Diluted Shares Outstanding141.50
Fully Diluted Market Cap56,920.6
+Consolidated Debt240.1
−In-the-Money Convertible Debt—
+Capital Leases159.8
+Operating Leases—
−Cash & Equivalents-1,087.9
−Short-term Investments-
+Total Preferred-
−In-the-Money Convertible Preferred—
−Investments in Unconsolidated Subs—
+Non-Controlling Interest-
+Pension Liabilities—
Enterprise Value56,761.8

Segment data

Revenue

by Products and services

  • Product100%
  • Licensing And Other0%

Revenue

by Geography

  • United States98%
  • Europe, Middle East, India, And Africa1%
  • Americas, Excluding U.s.0%
  • Asia Pacific And Other0%

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