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Karyopharm Therapeutics Inc.(KPTI US)

$0.83+0.3573.35%Ext:$0.80-0.044.44%(After Hours · 23:25:17 UTC)
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SEC Filings
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KPTI US​
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SEC Filings by Owner

Insider Ownership

Shacham Sharon(69)

  • 4Statement of changes in beneficial ownership31 Mar 2022
  • 4Statement of changes in beneficial ownership2 Mar 2022
  • 4Statement of changes in beneficial ownership22 Feb 2022
  • 4Statement of changes in beneficial ownership9 Feb 2022
  • 4Statement of changes in beneficial ownership23 Mar 2021
  • 4Statement of changes in beneficial ownership1 Mar 2021
  • 4Statement of changes in beneficial ownership22 Feb 2021
  • 4Statement of changes in beneficial ownership17 Feb 2021
  • 4Statement of changes in beneficial ownership9 Feb 2021
  • 4Statement of changes in beneficial ownership14 Oct 2020

Kauffman Michael(68)

  • 4Statement of changes in beneficial ownership2 Mar 2022
  • 4Statement of changes in beneficial ownership22 Feb 2022
  • 4Statement of changes in beneficial ownership9 Feb 2022
  • 4Statement of changes in beneficial ownership23 Mar 2021
  • 4Statement of changes in beneficial ownership1 Mar 2021
  • 4Statement of changes in beneficial ownership22 Feb 2021
  • 4Statement of changes in beneficial ownership17 Feb 2021
  • 4Statement of changes in beneficial ownership9 Feb 2021
  • 4Statement of changes in beneficial ownership14 Oct 2020
  • 4Statement of changes in beneficial ownership18 Aug 2020

Paulson Richard A.(52)

  • 4Statement of changes in beneficial ownership15 May
  • 4Statement of changes in beneficial ownership3 Mar
  • 4Statement of changes in beneficial ownership9 Feb
  • 4Statement of changes in beneficial ownership16 Oct 2025
  • 4Statement of changes in beneficial ownership16 Sep 2025
  • 4Statement of changes in beneficial ownership7 May 2025
  • 4Statement of changes in beneficial ownership7 Apr 2025
  • 4Statement of changes in beneficial ownership6 Mar 2025
  • 4Statement of changes in beneficial ownership4 Mar 2025
  • 4Statement of changes in beneficial ownership5 Feb 2025

Hadjimichael Andreas(47)

  • 4OWNERSHIP DOCUMENT4 Mar 2019
  • 4OWNERSHIP DOCUMENT27 Feb 2019
  • 4OWNERSHIP DOCUMENT7 Sep 2018
  • 4OWNERSHIP DOCUMENT4 Sep 2018
  • 4OWNERSHIP DOCUMENT29 Aug 2018
  • 4OWNERSHIP DOCUMENT14 Aug 2018
  • 4OWNERSHIP DOCUMENT9 Aug 2018
  • 4OWNERSHIP DOCUMENT25 Jul 2018
  • 4Statement of changes in beneficial ownership23 Jul 2018
  • 4OWNERSHIP DOCUMENT18 Jul 2018

Czernik Marcin(47)

  • 4OWNERSHIP DOCUMENT4 Mar 2019
  • 4OWNERSHIP DOCUMENT27 Feb 2019
  • 4OWNERSHIP DOCUMENT7 Sep 2018
  • 4OWNERSHIP DOCUMENT4 Sep 2018
  • 4OWNERSHIP DOCUMENT29 Aug 2018
  • 4OWNERSHIP DOCUMENT14 Aug 2018
  • 4OWNERSHIP DOCUMENT9 Aug 2018
  • 4OWNERSHIP DOCUMENT25 Jul 2018
  • 4Statement of changes in beneficial ownership23 Jul 2018
  • 4OWNERSHIP DOCUMENT18 Jul 2018

Mirza Mansoor Raza(37)

  • 4Statement of changes in beneficial ownership29 May 2025
  • 4Statement of changes in beneficial ownership30 May 2024
  • 4Statement of changes in beneficial ownership25 May 2023
  • 4Statement of changes in beneficial ownership20 May 2022
  • 4Statement of changes in beneficial ownership21 May 2021
  • 4Statement of changes in beneficial ownership22 Dec 2020
  • 4Statement of changes in beneficial ownership8 Dec 2020
  • 4Statement of changes in beneficial ownership26 May 2020
  • 4Statement of changes in beneficial ownership4 Mar 2020
  • 4Statement of changes in beneficial ownership13 Jan 2020

Primiano Christopher Brett(35)

  • 4Statement of changes in beneficial ownership3 Dec 2020
  • 4Statement of changes in beneficial ownership4 Nov 2020
  • 4Statement of changes in beneficial ownership14 Oct 2020
  • 4Statement of changes in beneficial ownership10 Sep 2020
  • 4Statement of changes in beneficial ownership11 May 2020
  • 4Statement of changes in beneficial ownership4 Mar 2020
  • 4Statement of changes in beneficial ownership21 Feb 2020
  • 4Statement of changes in beneficial ownership19 Feb 2020
  • 4Statement of changes in beneficial ownership7 Feb 2020
  • 4Statement of changes in beneficial ownership31 Dec 2019

Chione Ltd(31)

  • 4OWNERSHIP DOCUMENT4 Mar 2019
  • 4OWNERSHIP DOCUMENT27 Feb 2019
  • 4OWNERSHIP DOCUMENT7 Sep 2018
  • 4OWNERSHIP DOCUMENT4 Sep 2018
  • 4OWNERSHIP DOCUMENT29 Aug 2018
  • 4OWNERSHIP DOCUMENT14 Aug 2018
  • 4OWNERSHIP DOCUMENT9 Aug 2018
  • 4OWNERSHIP DOCUMENT25 Jul 2018
  • 4Statement of changes in beneficial ownership23 Jul 2018
  • 4OWNERSHIP DOCUMENT18 Jul 2018

Smolokowski Wiaczeslaw(31)

  • 4OWNERSHIP DOCUMENT4 Mar 2019
  • 4OWNERSHIP DOCUMENT27 Feb 2019
  • 4OWNERSHIP DOCUMENT7 Sep 2018
  • 4OWNERSHIP DOCUMENT4 Sep 2018
  • 4OWNERSHIP DOCUMENT29 Aug 2018
  • 4OWNERSHIP DOCUMENT14 Aug 2018
  • 4OWNERSHIP DOCUMENT9 Aug 2018
  • 4OWNERSHIP DOCUMENT25 Jul 2018
  • 4Statement of changes in beneficial ownership23 Jul 2018
  • 4OWNERSHIP DOCUMENT18 Jul 2018

Hadjimichael Amalia(26)

  • 4OWNERSHIP DOCUMENT1 Dec 2014
  • 4OWNERSHIP DOCUMENT25 Nov 2014
  • 4OWNERSHIP DOCUMENT20 Nov 2014
  • 4OWNERSHIP DOCUMENT12 Nov 2014
  • 4OWNERSHIP DOCUMENT6 Nov 2014
  • 4OWNERSHIP DOCUMENT30 Sep 2014
  • 4OWNERSHIP DOCUMENT30 Sep 2014
  • 4OWNERSHIP DOCUMENT26 Sep 2014
  • 4OWNERSHIP DOCUMENT19 Sep 2014
  • 4OWNERSHIP DOCUMENT16 Sep 2014

Frenkel Ran(23)

  • 4Statement of changes in beneficial ownership2 Mar 2022
  • 4Statement of changes in beneficial ownership22 Feb 2022
  • 4Statement of changes in beneficial ownership9 Feb 2022
  • 4Statement of changes in beneficial ownership1 Mar 2021
  • 4Statement of changes in beneficial ownership22 Feb 2021
  • 4Statement of changes in beneficial ownership17 Feb 2021
  • 4Statement of changes in beneficial ownership9 Feb 2021
  • 4Statement of changes in beneficial ownership11 May 2020
  • 4Statement of changes in beneficial ownership21 Feb 2020
  • 4Statement of changes in beneficial ownership19 Feb 2020

Mason Michael(22)

  • 4Statement of changes in beneficial ownership5 Sep 2024
  • 4Statement of changes in beneficial ownership6 Jun 2024
  • 4Statement of changes in beneficial ownership4 Mar 2024
  • 4Statement of changes in beneficial ownership27 Feb 2024
  • 4Statement of changes in beneficial ownership8 Feb 2024
  • 4Statement of changes in beneficial ownership25 Jan 2024
  • 4Statement of changes in beneficial ownership5 Sep 2023
  • 4Statement of changes in beneficial ownership5 Jun 2023
  • 4Statement of changes in beneficial ownership2 Mar 2023
  • 4Statement of changes in beneficial ownership1 Mar 2023

PAKIANATHAN DEEPIKA(21)

  • 4Statement of changes in beneficial ownership26 May
  • 4Statement of changes in beneficial ownership29 May 2025
  • 4Statement of changes in beneficial ownership7 Jun 2024
  • 4Statement of changes in beneficial ownership4 Jun 2024
  • 4Statement of changes in beneficial ownership30 May 2024
  • 4Statement of changes in beneficial ownership25 May 2023
  • 4Statement of changes in beneficial ownership10 Jun 2022
  • 4Statement of changes in beneficial ownership20 May 2022
  • 4Statement of changes in beneficial ownership21 May 2021
  • 4Statement of changes in beneficial ownership26 May 2020

Hadjimichael George(21)

  • 4OWNERSHIP DOCUMENT4 Mar 2019
  • 4OWNERSHIP DOCUMENT27 Feb 2019
  • 4OWNERSHIP DOCUMENT7 Sep 2018
  • 4OWNERSHIP DOCUMENT4 Sep 2018
  • 4OWNERSHIP DOCUMENT29 Aug 2018
  • 4OWNERSHIP DOCUMENT14 Aug 2018
  • 4OWNERSHIP DOCUMENT9 Aug 2018
  • 4OWNERSHIP DOCUMENT25 Jul 2018
  • 4Statement of changes in beneficial ownership23 Jul 2018
  • 4OWNERSHIP DOCUMENT18 Jul 2018

Poulton Stuart(20)

  • 4Statement of changes in beneficial ownership30 Jul
  • 4Statement of changes in beneficial ownership15 May
  • 4Statement of changes in beneficial ownership3 Mar
  • 4Statement of changes in beneficial ownership19 Feb
  • 4Statement of changes in beneficial ownership3 Feb
  • 4Statement of changes in beneficial ownership16 Oct 2025
  • 4Statement of changes in beneficial ownership16 Sep 2025
  • 4Statement of changes in beneficial ownership30 Jul 2025
  • 4Statement of changes in beneficial ownership6 Mar 2025
  • 4Statement of changes in beneficial ownership4 Mar 2025

Cheng Sohanya Roshan(19)

  • 4Statement of changes in beneficial ownership15 May
  • 4Statement of changes in beneficial ownership3 Mar
  • 4Statement of changes in beneficial ownership3 Feb
  • 4Statement of changes in beneficial ownership16 Oct 2025
  • 4Statement of changes in beneficial ownership16 Sep 2025
  • 4Statement of changes in beneficial ownership6 Mar 2025
  • 4Statement of changes in beneficial ownership4 Mar 2025
  • 4Statement of changes in beneficial ownership5 Sep 2024
  • 4Statement of changes in beneficial ownership4 Mar 2024
  • 4Statement of changes in beneficial ownership28 Feb 2024

Greene Barry E(17)

  • 4Statement of changes in beneficial ownership26 May
  • 4Statement of changes in beneficial ownership29 May 2025
  • 4Statement of changes in beneficial ownership30 May 2024
  • 4Statement of changes in beneficial ownership25 May 2023
  • 4Statement of changes in beneficial ownership15 Aug 2022
  • 4Statement of changes in beneficial ownership20 May 2022
  • 4Statement of changes in beneficial ownership21 May 2021
  • 4Statement of changes in beneficial ownership26 May 2020
  • 4Statement of changes in beneficial ownership17 Mar 2020
  • 4Statement of changes in beneficial ownership7 Jun 2019

BOHLIN GAREN G(16)

  • 4Statement of changes in beneficial ownership26 May
  • 4Statement of changes in beneficial ownership29 May 2025
  • 4Statement of changes in beneficial ownership30 May 2024
  • 4Statement of changes in beneficial ownership12 Sep 2023
  • 4Statement of changes in beneficial ownership25 May 2023
  • 4Statement of changes in beneficial ownership20 May 2022
  • 4Statement of changes in beneficial ownership21 May 2021
  • 4Statement of changes in beneficial ownership10 May 2021
  • 4Statement of changes in beneficial ownership26 May 2020
  • 4Statement of changes in beneficial ownership7 Jun 2019

Rangwala Reshma(16)

  • 4Statement of changes in beneficial ownership15 May
  • 4Statement of changes in beneficial ownership22 Apr
  • 4Statement of changes in beneficial ownership3 Mar
  • 4Statement of changes in beneficial ownership3 Feb
  • 4Statement of changes in beneficial ownership16 Sep 2025
  • 4Statement of changes in beneficial ownership24 Apr 2025
  • 4Statement of changes in beneficial ownership6 Mar 2025
  • 4Statement of changes in beneficial ownership4 Mar 2025
  • 4Statement of changes in beneficial ownership23 Apr 2024
  • 4Statement of changes in beneficial ownership4 Mar 2024

Mano Michael(16)

  • 4Statement of changes in beneficial ownership15 May
  • 4Statement of changes in beneficial ownership3 Mar
  • 4Statement of changes in beneficial ownership3 Feb
  • 4Statement of changes in beneficial ownership16 Oct 2025
  • 4Statement of changes in beneficial ownership16 Sep 2025
  • 4Statement of changes in beneficial ownership6 Mar 2025
  • 4Statement of changes in beneficial ownership4 Mar 2025
  • 4Statement of changes in beneficial ownership5 Sep 2024
  • 4Statement of changes in beneficial ownership4 Mar 2024
  • 4Statement of changes in beneficial ownership28 Feb 2024

Abate Kristin(15)

  • 4Statement of changes in beneficial ownership19 Oct
  • 4Statement of changes in beneficial ownership2 Oct
  • 4Statement of changes in beneficial ownership2 Sep
  • 4Statement of changes in beneficial ownership15 May
  • 4Statement of changes in beneficial ownership3 Mar
  • 4Statement of changes in beneficial ownership29 Jan
  • 4Statement of changes in beneficial ownership22 Jan
  • 4Statement of changes in beneficial ownership16 Oct 2025
  • 4Statement of changes in beneficial ownership3 Oct 2025
  • 4Statement of changes in beneficial ownership16 Sep 2025

Shah Jatin(14)

  • 4Statement of changes in beneficial ownership22 Feb 2022
  • 4Statement of changes in beneficial ownership9 Feb 2022
  • 4Statement of changes in beneficial ownership13 Jul 2021
  • 4Statement of changes in beneficial ownership11 May 2021
  • 4Statement of changes in beneficial ownership1 Mar 2021
  • 4Statement of changes in beneficial ownership22 Feb 2021
  • 4Statement of changes in beneficial ownership17 Feb 2021
  • 4Statement of changes in beneficial ownership9 Feb 2021
  • 4Statement of changes in beneficial ownership4 Nov 2020
  • 4Statement of changes in beneficial ownership21 Feb 2020

Dolsten Mikael(9)

  • 4Statement of changes in beneficial ownership21 May 2021
  • 4Statement of changes in beneficial ownership26 May 2020
  • 4Statement of changes in beneficial ownership7 Jun 2019
  • 4Statement of changes in beneficial ownership20 Jun 2018
  • 4Statement of changes in beneficial ownership16 Jun 2017
  • 4Statement of changes in beneficial ownership17 Jun 2016
  • 4Statement of changes in beneficial ownership26 May 2015
  • 4Statement of changes in beneficial ownership2 Apr 2015
  • 3Initial statement of beneficial ownership2 Apr 2015

Renz Justin A(9)

  • 4Statement of changes in beneficial ownership24 Jan 2017
  • 4Statement of changes in beneficial ownership14 Nov 2016
  • 4Statement of changes in beneficial ownership8 Nov 2016
  • 4Statement of changes in beneficial ownership20 Jan 2016
  • 4Statement of changes in beneficial ownership9 Nov 2015
  • 4Statement of changes in beneficial ownership6 Apr 2015
  • 4Statement of changes in beneficial ownership22 Jan 2015
  • 4Statement of changes in beneficial ownership15 Sep 2014
  • 3Initial statement of beneficial ownership27 Aug 2014

Schor Chen(8)

  • 4Statement of changes in beneficial ownership26 May
  • 4Statement of changes in beneficial ownership29 May 2025
  • 4Statement of changes in beneficial ownership30 May 2024
  • 4Statement of changes in beneficial ownership25 May 2023
  • 4Statement of changes in beneficial ownership20 May 2022
  • 4Statement of changes in beneficial ownership21 May 2021
  • 3Initial statement of beneficial ownership30 Nov 2020
  • 4Statement of changes in beneficial ownership30 Nov 2020

Oliger Christy J.(8)

  • 4Statement of changes in beneficial ownership26 May
  • 4Statement of changes in beneficial ownership29 May 2025
  • 4Statement of changes in beneficial ownership30 May 2024
  • 4Statement of changes in beneficial ownership25 May 2023
  • 4Statement of changes in beneficial ownership20 May 2022
  • 4Statement of changes in beneficial ownership21 May 2021
  • 4Statement of changes in beneficial ownership31 Aug 2020
  • 3Initial statement of beneficial ownership31 Aug 2020

Garland J. Scott(7)

  • 4Statement of changes in beneficial ownership7 Jun 2019
  • 4Statement of changes in beneficial ownership20 Jun 2018
  • 4Statement of changes in beneficial ownership16 Jun 2017
  • 4Statement of changes in beneficial ownership17 Jun 2016
  • 4Statement of changes in beneficial ownership26 May 2015
  • 4Statement of changes in beneficial ownership12 Nov 2014
  • 3Initial statement of beneficial ownership12 Nov 2014

Mitchener Stephen(7)

  • 4Statement of changes in beneficial ownership2 Mar 2023
  • 4Statement of changes in beneficial ownership1 Sep 2022
  • 4Statement of changes in beneficial ownership2 Mar 2022
  • 4Statement of changes in beneficial ownership3 Dec 2021
  • 4Statement of changes in beneficial ownership3 Jun 2021
  • 4Statement of changes in beneficial ownership1 Jun 2021
  • 3Initial statement of beneficial ownership5 Jan 2021

WEG KENNETH E(6)

  • 4Statement of changes in beneficial ownership16 Jun 2017
  • 4Statement of changes in beneficial ownership17 Jun 2016
  • 4Statement of changes in beneficial ownership26 May 2015
  • 4Statement of changes in beneficial ownership6 Apr 2015
  • 4Statement of changes in beneficial ownership9 Jul 2014
  • 3Initial statement of beneficial ownership5 Nov 2013

Lewis Tanya(6)

  • 4Statement of changes in beneficial ownership1 Mar 2021
  • 4Statement of changes in beneficial ownership17 Feb 2021
  • 4Statement of changes in beneficial ownership9 Feb 2021
  • 4Statement of changes in beneficial ownership4 Nov 2020
  • 4Statement of changes in beneficial ownership7 Feb 2020
  • 3Initial statement of beneficial ownership5 Nov 2019

Brannelly Paul(5)

  • 4Statement of changes in beneficial ownership15 May 2014
  • 4Statement of changes in beneficial ownership14 May 2014
  • 4Statement of changes in beneficial ownership13 May 2014
  • 4Statement of changes in beneficial ownership20 Dec 2013
  • 3Initial statement of beneficial ownership5 Nov 2013

Macomber Lori(5)

  • 4Statement of changes in beneficial ownership4 Feb
  • 4Statement of changes in beneficial ownership3 Feb
  • 4Statement of changes in beneficial ownership16 Oct 2025
  • 4Statement of changes in beneficial ownership3 Feb 2025
  • 3Initial statement of beneficial ownership6 Jan 2025

Su Zhen(5)

  • 4Statement of changes in beneficial ownership26 May
  • 4Statement of changes in beneficial ownership29 May 2025
  • 4Statement of changes in beneficial ownership30 May 2024
  • 3Initial statement of beneficial ownership1 Sep 2023
  • 4Statement of changes in beneficial ownership1 Sep 2023

Honig Peter(4)

  • 4Statement of changes in beneficial ownership25 May 2023
  • 4Statement of changes in beneficial ownership20 May 2022
  • 4Statement of changes in beneficial ownership7 Dec 2021
  • 3Initial statement of beneficial ownership7 Dec 2021

Plio Ltd(4)

  • 4/AAMENDMENT TO OWNERSHIP DOCUMENT28 Jul 2014
  • 4OWNERSHIP DOCUMENT25 Jul 2014
  • 4OWNERSHIP DOCUMENT15 Nov 2013
  • 3OWNERSHIP DOCUMENT8 Nov 2013

Jankilevitsch Gregory(4)

  • 4/AAMENDMENT TO OWNERSHIP DOCUMENT28 Jul 2014
  • 4OWNERSHIP DOCUMENT25 Jul 2014
  • 4OWNERSHIP DOCUMENT15 Nov 2013
  • 3OWNERSHIP DOCUMENT8 Nov 2013

DEMAREE JOHN(4)

  • 4Statement of changes in beneficial ownership1 Mar 2021
  • 4Statement of changes in beneficial ownership27 Aug 2020
  • 4Statement of changes in beneficial ownership17 Mar 2020
  • 3Initial statement of beneficial ownership17 Mar 2020

FALVEY MICHAEL(3)

  • 4Statement of changes in beneficial ownership25 Jan 2018
  • 4Statement of changes in beneficial ownership13 Sep 2017
  • 3Initial statement of beneficial ownership13 Sep 2017

Varadan Anand(3)

  • 4Statement of changes in beneficial ownership19 Feb 2019
  • 3Initial statement of beneficial ownership25 Jun 2018
  • 4Statement of changes in beneficial ownership25 Jun 2018

Thiel Carsten(2)

  • 4Statement of changes in beneficial ownership4 Sep 2018
  • 3Initial statement of beneficial ownership4 Sep 2018

Peters Cameron(2)

  • 4Statement of changes in beneficial ownership19 Feb 2019
  • 3Initial statement of beneficial ownership24 Jan 2019

Todisco Michael(1)

  • 3Initial statement of beneficial ownership10 Apr 2017

≥5% Ownership

BlackRock Inc.(13)

  • SC 13G/AKaryopharm Therapeutics Inc.8 Jul 2024
  • SC 13G/AKaryopharm Therapeutics Inc.25 Jan 2024
  • SC 13G/AKaryopharm Therapeutics Inc.26 Jan 2023
  • SC 13GKaryopharm Therapeutics Inc.20 Jan 2023
  • SC 13GKaryopharm Therapeutics Inc.27 Jan 2022
  • SC 13G/AKaryopharm Therapeutics Inc.26 Jan 2022
  • SC 13G/AKaryopharm Therapeutics Inc.27 Jan 2021
  • SC 13GKaryopharm Therapeutics Inc.8 Dec 2020
  • SC 13G/AKaryopharm Therapeutics Inc.5 Feb 2020
  • SC 13G/AKaryopharm Therapeutics Inc.6 Feb 2019

Palo Alto Investors LP(9)

  • SC 13G/AKaryopharm Therapeutics Inc.14 Feb 2024
  • SC 13G/AKaryopharm Therapeutics Inc.14 Feb 2023
  • SC 13G/AKaryopharm Therapeutics Inc.14 Feb 2022
  • SC 13G/AKaryopharm Therapeutics Inc.16 Feb 2021
  • SC 13G/AKaryopharm Therapeutics Inc.14 Feb 2020
  • SC 13G/AKaryopharm Therapeutics Inc.14 Feb 2019
  • SC 13G/AKaryopharm Therapeutics Inc.14 Feb 2018
  • SC 13G/AKaryopharm Therapeutics Inc.12 Jan 2017
  • SC 13GKaryopharm Therapeutics Inc.16 Feb 2016

Kauffman Michael(9)

  • SC 13G/AKaryopharm Therapeutics Inc.11 Feb 2022
  • SC 13G/AKaryopharm Therapeutics Inc.16 Feb 2021
  • SC 13G/AKaryopharm Therapeutics Inc.13 Feb 2020
  • SC 13G/AKaryopharm Therapeutics Inc.11 Feb 2019
  • SC 13G/AKaryopharm Therapeutics Inc.13 Feb 2018
  • SC 13G/AKaryopharm Therapeutics Inc.14 Feb 2017
  • SC 13G/AKaryopharm Therapeutics Inc.12 Feb 2016
  • SC 13G/AKaryopharm Therapeutics Inc.13 Feb 2015
  • SC 13GKaryopharm Therapeutics Inc.14 Feb 2014

Chione Ltd(9)

  • SC 13G/AKaryopharm Therapeutics Inc.14 Feb 2023
  • SC 13G/AKaryopharm Therapeutics Inc.11 Feb 2022
  • SC 13G/AKaryopharm Therapeutics Inc.16 Feb 2021
  • SC 13G/AKaryopharm Therapeutics Inc.14 Feb 2020
  • SC 13G/AKaryopharm Therapeutics Inc.13 Feb 2019
  • SC 13G/AKaryopharm Therapeutics Inc.14 Feb 2018
  • SC 13G/AKaryopharm Therapeutics Inc.13 Feb 2017
  • SC 13G/AKaryopharm Therapeutics Inc.9 Mar 2016
  • SC 13GKaryopharm Therapeutics Inc.18 Feb 2014

FRANKLIN RESOURCES INC(7)

  • SC 13G/AKaryopharm Therapeutics Inc.28 Jan 2019
  • SC 13G/AKaryopharm Therapeutics Inc.7 Feb 2018
  • SC 13G/AKaryopharm Therapeutics Inc.7 Feb 2017
  • SC 13G/AKaryopharm Therapeutics Inc.9 May 2016
  • SC 13G/AKaryopharm Therapeutics Inc.9 Feb 2016
  • SC 13G/AKaryopharm Therapeutics Inc.9 Feb 2015
  • SC 13GKaryopharm Therapeutics Inc.10 Jun 2014

STATE STREET CORP(7)

  • SC 13G/AKaryopharm Therapeutics Inc.22 Jan 2024
  • SC 13G/AKaryopharm Therapeutics Inc.10 Jul 2023
  • SC 13G/AKaryopharm Therapeutics Inc.2 Feb 2023
  • SC 13G/AKaryopharm Therapeutics Inc.11 Feb 2022
  • SC 13G/AKaryopharm Therapeutics Inc.12 Oct 2021
  • SC 13GKaryopharm Therapeutics Inc.11 Feb 2021
  • SC 13GKaryopharm Therapeutics Inc.13 Feb 2020

FMR LLC(7)

  • SC 13G/AKaryopharm Therapeutics Inc.10 May 2018
  • SC 13G/AKaryopharm Therapeutics Inc.13 Feb 2018
  • SC 13G/AKaryopharm Therapeutics Inc.14 Feb 2017
  • SC 13G/AKaryopharm Therapeutics Inc.12 Feb 2016
  • SC 13G/AKaryopharm Therapeutics Inc.13 Feb 2015
  • SC 13G/AKaryopharm Therapeutics Inc.10 Jul 2014
  • SC 13GKaryopharm Therapeutics Inc.14 Feb 2014

INTEGRATED CORE STRATEGIES (US) LLC(6)

  • SC 13G/AKaryopharm Therapeutics Inc.05:34PM
  • SC 13GKaryopharm Therapeutics Inc.4 Sep
  • SC 13G/AKaryopharm Therapeutics Inc.13 Apr
  • SC 13GKaryopharm Therapeutics Inc.10 Feb
  • SC 13G/AKaryopharm Therapeutics Inc.6 Feb 2020
  • SC 13GKaryopharm Therapeutics Inc.23 Jul 2019

WELLINGTON MANAGEMENT GROUP LLP(5)

  • SC 13G/AKaryopharm Therapeutics Inc.8 Nov 2019
  • SC 13G/AKaryopharm Therapeutics Inc.12 Feb 2019
  • SC 13G/AKaryopharm Therapeutics Inc.8 Feb 2018
  • SC 13G/AKaryopharm Therapeutics Inc.9 Feb 2017
  • SC 13GKaryopharm Therapeutics Inc.11 Oct 2016

Point72 Asset Management, L.P.(5)

  • SC 13G/AKaryopharm Therapeutics Inc.14 Feb 2020
  • SC 13GKaryopharm Therapeutics Inc.27 Feb 2019
  • SC 13G/AKaryopharm Therapeutics Inc.14 Feb 2019
  • SC 13G/AKaryopharm Therapeutics Inc.14 Feb 2018
  • SC 13GKaryopharm Therapeutics Inc.6 Nov 2017

VANGUARD GROUP INC(4)

  • SC 13G/AKaryopharm Therapeutics Inc.30 Oct 2025
  • SC 13G/AKaryopharm Therapeutics Inc.12 Nov 2024
  • SC 13G/AKaryopharm Therapeutics Inc.4 Nov 2024
  • SC 13GKaryopharm Therapeutics Inc.13 Feb 2024

Adage Capital Management, L.P.(4)

  • SC 13G/AKaryopharm Therapeutics Inc.12 Aug
  • SC 13GKaryopharm Therapeutics Inc.13 May
  • SC 13G/AKaryopharm Therapeutics Inc.12 Feb
  • SC 13GKaryopharm Therapeutics Inc.12 Feb 2025

Consonance Capital Management LP(4)

  • SC 13G/AKaryopharm Therapeutics Inc.17 Feb 2021
  • SC 13G/AKaryopharm Therapeutics Inc.16 Feb 2021
  • SC 13G/AKaryopharm Therapeutics Inc.14 Feb 2020
  • SC 13GKaryopharm Therapeutics Inc.14 Feb 2019

ACORN BIOVENTURES, L.P.(4)

  • SC 13G/AKaryopharm Therapeutics Inc.8 Oct
  • SC 13G/AKaryopharm Therapeutics Inc.25 Sep
  • SC 13G/AKaryopharm Therapeutics Inc.25 Sep
  • SC 13GKaryopharm Therapeutics Inc.15 May

Commodore Capital LP(4)

  • SC 13G/AKaryopharm Therapeutics Inc.14 Aug
  • SC 13GKaryopharm Therapeutics Inc.2 Apr
  • SC 13G/AKaryopharm Therapeutics Inc.14 Feb 2023
  • SC 13GKaryopharm Therapeutics Inc.9 May 2022

T. Rowe Price Investment Management, Inc.(4)

  • SC 13G/AKaryopharm Therapeutics Inc.5 Jun
  • SC 13G/AKaryopharm Therapeutics Inc.17 Feb
  • SC 13G/AKaryopharm Therapeutics Inc.7 Nov 2025
  • SC 13GKaryopharm Therapeutics Inc.14 Aug 2025

ADAGE CAPITAL PARTNERS GP, L.L.C.(3)

  • SC 13G/AKaryopharm Therapeutics Inc.11 Feb 2021
  • SC 13G/AKaryopharm Therapeutics Inc.12 Feb 2020
  • SC 13GKaryopharm Therapeutics Inc.18 Nov 2019

Ridgeback Capital Investments L.P.(3)

  • SC 13G/AKaryopharm Therapeutics Inc.14 Feb 2020
  • SC 13G/AKaryopharm Therapeutics Inc.14 Feb 2019
  • SC 13GKaryopharm Therapeutics Inc.26 Jan 2018

DELPHI VENTURES VIII LP(3)

  • SC 13D/AKaryopharm Therapeutics Inc.7 Jun 2017
  • SC 13D/AKaryopharm Therapeutics Inc.14 Feb 2017
  • SC 13DKaryopharm Therapeutics Inc.15 Nov 2013

Affinity Asset Advisors, LLC(3)

  • SC 13G/AKaryopharm Therapeutics Inc.14 May
  • SC 13G/AKaryopharm Therapeutics Inc.29 Jan
  • SC 13GKaryopharm Therapeutics Inc.10 Apr 2025

Avidity Partners Management LP(3)

  • SC 13G/AKaryopharm Therapeutics Inc.14 Nov 2024
  • SC 13G/AKaryopharm Therapeutics Inc.14 Feb 2024
  • SC 13G/AKaryopharm Therapeutics Inc.14 Feb 2023

JPMORGAN CHASE & CO(2)

  • SC 13G/AKaryopharm Therapeutics Inc.17 Oct 2025
  • SC 13GKaryopharm Therapeutics Inc.16 Jul 2025

GOLDMAN SACHS GROUP INC(2)

  • SC 13G/AKaryopharm Therapeutics Inc.11 Aug
  • SC 13GKaryopharm Therapeutics Inc.12 May

HIGHBRIDGE CAPITAL MANAGEMENT LLC(2)

  • SC 13G/AKaryopharm Therapeutics Inc.14 Nov 2025
  • SC 13GKaryopharm Therapeutics Inc.25 Oct 2024

RA CAPITAL MANAGEMENT, L.P.(2)

  • SC 13G/AKaryopharm Therapeutics Inc.14 Aug
  • SC 13GKaryopharm Therapeutics Inc.2 Apr

Foresite Capital Fund I, L.P.(2)

  • SC 13G/AKaryopharm Therapeutics Inc.11 Feb 2015
  • SC 13GKaryopharm Therapeutics Inc.15 Nov 2013

J. WOOD CAPITAL ADVISORS LLC(2)

  • SC 13G/AKaryopharm Therapeutics Inc.3 Nov 2025
  • SC 13GKaryopharm Therapeutics Inc.23 May 2024

Plio Ltd(2)

  • SC 13G/AKaryopharm Therapeutics Inc.23 Feb 2016
  • SC 13GKaryopharm Therapeutics Inc.18 Feb 2014

Opaleye Management Inc.(2)

  • SC 13G/AKaryopharm Therapeutics Inc.11 May
  • SC 13GKaryopharm Therapeutics Inc.17 Oct 2025

Avoro Capital Advisors LLC(2)

  • SC 13G/AKaryopharm Therapeutics Inc.12 Feb 2021
  • SC 13GKaryopharm Therapeutics Inc.14 Feb 2020

Rubric Capital Management LP(2)

  • SC 13G/AKaryopharm Therapeutics Inc.12 Feb 2024
  • SC 13GKaryopharm Therapeutics Inc.10 Feb 2023

Ikarian Capital, LLC(1)

  • SC 13GKaryopharm Therapeutics Inc.15 May

BlackRock, Inc.(1)

  • SC 13GKaryopharm Therapeutics Inc.28 Jul